PCAT1 · rs182352457
Where this position leads
Condition: Prostate Cancer
What the study found
Who was studied 7,822 European ancestry cases, 144,172 European ancestry controls.
The effect Each copy of the A allele shifted the measure 0.88 higher (95% confidence interval 0.69-1.07); p = 3 × 10−19.
Where it sits Chromosome 8, band 8q24.21 — in an intron of PCAT1.
What ClinVar records
Classification
association for Familial prostate cancer; no assertion criteria provided (0 of 4 stars, 1 submitter).
ClinVar record 979038 NC_000008.11:g.126929548G>A
What this is ClinVar's aggregate record for this position (as of its 2026-10-19 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.
rs182352457 is a single position in the genome, in or near the PCAT1 gene. Published research associates it with prostate cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
On MyGeneLog this position is linked to Prostate Cancer. The research behind each link, and its sources, are set out on that condition page.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Scientific reports 2024, PMID:38538606. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Prostate cancer (rs182352457). MyGeneLog™. https://www.mygenelog.com/variants/rs182352457