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Daytime nap

FGF4 · rs182197129

Where this position leads

What the study found

Who was studied 113,054 European ancestry cases and controls.

The effect Each copy of the T allele shifted the measure 0.3 higher (95% confidence interval 0.21-0.39); p = 7 × 10⁻¹⁰.

How common The T allele had a frequency of about 0% in the people studied.

Where it sits Chromosome 11, band 11q13.3 — in the 3′ untranslated region of FGF4.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Daytime nap — no copies of the reported risk allele.

C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Daytime nap.

T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Daytime nap compared to the general population.

Source

Genome-wide association analysis of insomnia complaints identifies risk genes and genetic overlap with psychiatric and metabolic traits

Hammerschlag AR, Stringer S, de Leeuw CA, Sniekers S, Taskesen E, Watanabe K, Blanken TF, Dekker K, Te Lindert BHW, Wassing R, Jonsdottir I, Thorleifsson G

and 10 more — show all

Stefansson H, Gislason T, Berger K, Schormair B, Wellmann J, Winkelmann J, Stefansson K, Oexle K, Van Someren EJW, Posthuma D

Nature genetics · 2017 · PMID 28604731 · open access

Questions about rs182197129

What is rs182197129?

rs182197129 is a single position in the genome, in or near the FGF4 gene. Published research associates it with daytime nap. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs182197129 linked to?

On MyGeneLog this position is linked to Sleep and Circadian Rhythm. The research behind each link, and its sources, are set out on that condition page.

Does having rs182197129 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs182197129 come from?

GWAS Catalog, Nat Genet 2017, PMID:28604731. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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