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Omega-3 fatty acids to Omega-6 fatty acids ratio

TKFC · rs181955759

What the study found

Who was studied 239,268 European ancestry individuals.

The effect The reported allele is A; the catalogue records no effect size ; p = 4 × 10−13.

Where it sits Chromosome 11, band 11q12.2 — in an intron of TKFC.

What each result means

A/A Two copies of the version the research linked to Omega-3 fatty acids to Omega-6 fatty acids ratio. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Omega-3 fatty acids to Omega-6 fatty acids ratio. That is a smaller link than two copies.
G/G No copy of the version the research linked to Omega-3 fatty acids to Omega-6 fatty acids ratio. This is the starting point the study compared everyone against.
Source

Questions about rs181955759

What is rs181955759?

rs181955759 is a single position in the genome, in or near the TKFC gene. Published research associates it with omega-3 fatty acids to omega-6 fatty acids ratio. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs181955759 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs181955759 come from?

GWAS Catalog, HGG advances 2025, PMID:40545721. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Omega-3 fatty acids to Omega-6 fatty acids ratio (rs181955759). MyGeneLog™. https://www.mygenelog.com/variants/rs181955759

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