Parkinson's disease or first degree relation to individual with Parkinson's disease
FGD4 · rs181609621
0 231911317Reads by AI crawlersClaude0ChatGPT0Google · Gemini1Perplexity0Meta AI9Microsoft · Copilot1Amazon1Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others7Total23Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 15,056 European ancestry cases, 18,618 European ancestry proxy cases, 449,056 European ancestry controls; replicated in 22,632 European ancestry cases, 968,735 European ancestry controls.
The effect
Each copy of the A allele shifted the measure 0.423 lower (95% confidence interval 0.3-0.55); p = 8 × 10−11.
How common The A allele had a frequency of about 99% in the people studied.
Where it sits Chromosome 12, band 12p11.21 — between genes, 5.5 kb from LOC124902914.
What each result means
A/ATwo copies of the version the research linked to Parkinson's disease or first degree relation to individual with Parkinson's disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/COne copy of the version the research linked to Parkinson's disease or first degree relation to individual with Parkinson's disease. That is a smaller link than two copies.
C/CNo copy of the version the research linked to Parkinson's disease or first degree relation to individual with Parkinson's disease. This is the starting point the study compared everyone against.
rs181609621 is a single position in the genome, in or near the FGD4 gene. Published research associates it with parkinson's disease or first degree relation to individual with parkinson's disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs181609621 linked to?
On MyGeneLog this position is linked to Parkinson's Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs181609621 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs181609621 come from?
GWAS Catalog, Lancet Neurol 2019, PMID:31701892. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 231911317Reads by AI crawlersClaude0ChatGPT0Google · Gemini1Perplexity0Meta AI9Microsoft · Copilot1Amazon1Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others7Total23Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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Parkinson's disease or first degree relation to individual with Parkinson's disease (rs181609621). MyGeneLog™. https://www.mygenelog.com/variants/rs181609621