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Hair colour (natural, before greying): Light brown (UKB data field 1747_3)

OCA2 · rs181507749

What the study found

Who was studied 185,000 European ancestry cases, 270,164 European ancestry controls.

The effect Each copy of the G allele shifted the measure 0.47 lower (95% confidence interval 0.36-0.58); p = 5 × 10−16.

How common The G allele had a frequency of about 0% in the people studied.

Where it sits Chromosome 15, band 15q13.1 — in an intron of OCA2.

What each result means

A/A No copy of the version the research linked to Hair colour (natural, before greying): Light brown (UKB data field 1747_3). This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Hair colour (natural, before greying): Light brown (UKB data field 1747_3). That is a smaller link than two copies.
G/G Two copies of the version the research linked to Hair colour (natural, before greying): Light brown (UKB data field 1747_3). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs181507749

What is rs181507749?

rs181507749 is a single position in the genome, in or near the OCA2 gene. Published research associates it with hair colour (natural, before greying): light brown (ukb data field 1747_3). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs181507749 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs181507749 come from?

GWAS Catalog, Nature genetics 2021, PMID:34737426. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Hair colour (natural, before greying): Light brown (UKB data field 1747_3) (rs181507749). MyGeneLog™. https://www.mygenelog.com/variants/rs181507749

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