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Body mass index

near PKMP4 · rs1812736

Where this position leads

Conditions: Childhood Body Mass Index, Obesity and Body Weight

rs1812736 Condition: Childhood Body Mass Index Childhood Body Mass Index Condition Condition: Obesity and Body Weight Obesity and Body Weight Condition rs1812736 rs1812736 near PKMP4

What the study found

Who was studied 342,566 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0207 lower (95% confidence interval 0.014-0.027); p = 8 × 10−11.

Where it sits Chromosome 8, band 8q21.13 — between genes, 9.9 kb from PKMP4.

What each result means

A/A Two copies of the version the research linked to Body mass index. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Body mass index. That is a smaller link than two copies.
G/G No copy of the version the research linked to Body mass index. This is the starting point the study compared everyone against.
Source

Questions about rs1812736

What is rs1812736?

rs1812736 is a single position in the genome, in or near the near PKMP4 gene. Published research associates it with body mass index. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs1812736 linked to?

On MyGeneLog this position is linked to Childhood Body Mass Index, Obesity and Body Weight. The research behind each link, and its sources, are set out on that condition page.

Does having rs1812736 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1812736 come from?

GWAS Catalog, Scientific reports 2024, PMID:38538606. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Body mass index (rs1812736). MyGeneLog™. https://www.mygenelog.com/variants/rs1812736

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