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Who was studied 394,642 European ancestry individuals.
The effect
Each copy of the C allele shifted the measure 0.017 lower (95% confidence interval 0.012-0.022); p = 4 × 10−12.
How common The C allele had a frequency of about 20% in the people studied.
Where it sits Chromosome 22, band 22q13.1 — in an intron of TNRC6B.
What each result means
C/CTwo copies of the version the research linked to Diastolic blood pressure (UKB data field 4079). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Diastolic blood pressure (UKB data field 4079). That is a smaller link than two copies.
T/TNo copy of the version the research linked to Diastolic blood pressure (UKB data field 4079). This is the starting point the study compared everyone against.
Nature genetics · 2025 · PMID 39789286 · open access
Questions about rs1807579
What is rs1807579?
rs1807579 is a single position in the genome, in or near the TNRC6B gene. Published research associates it with diastolic blood pressure (ukb data field 4079). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs1807579 linked to?
On MyGeneLog this position is linked to Blood Pressure. The research behind each link, and its sources, are set out on that condition page.
Does having rs1807579 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1807579 come from?
GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Diastolic blood pressure (UKB data field 4079) (rs1807579). MyGeneLog™. https://www.mygenelog.com/variants/rs1807579