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Who was studied 474 African American or Afro-Caribbean cases, 55,031 African American or Afro-Caribbean controls, 2,951 European ancestry cases, 312,717 European ancestry controls, 274 Hispanic or Latin American cases, 29,040 Hispanic or Latin American controls.
The effect
Each copy of the T allele shifted the measure 2.55 lower (95% confidence interval 2.51-2.59); p = 8 × 10−12.
How common The T allele had a frequency of about 100% in the people studied.
Where it sits Chromosome 1, band 1q32.1 — in an intron of LEMD1-AS1.
What each result means
A/ANo copy of the version the research linked to Biological Grandparent (paternal): Asthma. This is the starting point the study compared everyone against.
A/TOne copy of the version the research linked to Biological Grandparent (paternal): Asthma. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Biological Grandparent (paternal): Asthma. That is the strongest link of the three results. A link in a study is not a diagnosis.
Science (New York, N.Y.) · 2024 · PMID 39024449 · open access
Questions about rs180737152
What is rs180737152?
rs180737152 is a single position in the genome, in or near the LEMD1-AS1 gene. Published research associates it with biological grandparent (paternal): asthma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs180737152 linked to?
On MyGeneLog this position is linked to Asthma. The research behind each link, and its sources, are set out on that condition page.
Does having rs180737152 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs180737152 come from?
GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 911223Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple2China (ByteDance, Huawei, Baidu…)0Others3Total9Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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