Standard

Mouth ulcers

IL19 · rs1800871

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What the study found

Who was studied 47,079 British or unknown ancestry cases, 414,027 British or unknown ancestry controls; replicated in 98,298 cases, 247,446 controls.

The effect Each copy of the G allele carried 1.18 times the odds of Mouth ulcers (95% confidence interval 1.17-1.19); p = 6 × 10⁻²³⁶.

How common The G allele had a frequency of about 24% in the people studied.

Where it sits Chromosome 1, band 1q32.1 — in an intron of IL19.

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Mouth ulcers — no copies of the reported risk allele.

A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Mouth ulcers.

G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Mouth ulcers compared to the general population.

Source

Genome wide analysis for mouth ulcers identifies associations at immune regulatory loci

Dudding T, Haworth S, Lind PA, Sathirapongsasuti JF, Tung JY, Mitchell R, Colodro-Conde L, Medland SE, Gordon S, Elsworth B, Paternoster L, Franks PW

and 3 more — show all

Thomas SJ, Martin NG, Timpson NJ

23andMe Research Team

Nature communications · 2019 · PMID 30837455 · open access

Questions about rs1800871

What is rs1800871?

rs1800871 is a single position in the genome, in or near the IL19 gene. Published research associates it with mouth ulcers. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs1800871 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1800871 come from?

GWAS Catalog, Nature communications 2019, PMID:30837455. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Mouth ulcers (rs1800871). MyGeneLog™. https://www.mygenelog.com/variants/rs1800871

← See all variants