Standard
Glycated hemoglobin levels
GCK · rs1799884
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
C/C
Published research associates this genotype with typical/baseline likelihood of Glycated hemoglobin levels — no copies of the reported risk allele. (GWAS Catalog, Diabetes 2010, PMID:20858683)
C/T
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Glycated hemoglobin levels. (GWAS Catalog, Diabetes 2010, PMID:20858683)
T/T
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Glycated hemoglobin levels compared to the general population. (GWAS Catalog, Diabetes 2010, PMID:20858683)
Source
Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways
Soranzo N,
Sanna S,
Wheeler E,
Gieger C,
Radke D,
Dupuis J,
Bouatia-Naji N,
Langenberg C,
Prokopenko I,
Stolerman E,
Sandhu MS,
Heeney MM
and 165 more — show all
Devaney JM,
Reilly MP,
Ricketts SL,
Stewart AF,
Voight BF,
Willenborg C,
Wright B,
Altshuler D,
Arking D,
Balkau B,
Barnes D,
Boerwinkle E,
Böhm B,
Bonnefond A,
Bonnycastle LL,
Boomsma DI,
Bornstein SR,
Böttcher Y,
Bumpstead S,
Burnett-Miller MS,
Campbell H,
Cao A,
Chambers J,
Clark R,
Collins FS,
Coresh J,
de Geus EJ,
Dei M,
Deloukas P,
Döring A,
Egan JM,
Elosua R,
Ferrucci L,
Forouhi N,
Fox CS,
Franklin C,
Franzosi MG,
Gallina S,
Goel A,
Graessler J,
Grallert H,
Greinacher A,
Hadley D,
Hall A,
Hamsten A,
Hayward C,
Heath S,
Herder C,
Homuth G,
Hottenga JJ,
Hunter-Merrill R,
Illig T,
Jackson AU,
Jula A,
Kleber M,
Knouff CW,
Kong A,
Kooner J,
Köttgen A,
Kovacs P,
Krohn K,
Kühnel B,
Kuusisto J,
Laakso M,
Lathrop M,
Lecoeur C,
Li M,
Li M,
Loos RJ,
Luan J,
Lyssenko V,
Mägi R,
Magnusson PK,
Mälarstig A,
Mangino M,
Martínez-Larrad MT,
März W,
McArdle WL,
McPherson R,
Meisinger C,
Meitinger T,
Melander O,
Mohlke KL,
Mooser VE,
Morken MA,
Narisu N,
Nathan DM,
Nauck M,
O'Donnell C,
Oexle K,
Olla N,
Pankow JS,
Payne F,
Peden JF,
Pedersen NL,
Peltonen L,
Perola M,
Polasek O,
Porcu E,
Rader DJ,
Rathmann W,
Ripatti S,
Rocheleau G,
Roden M,
Rudan I,
Salomaa V,
Saxena R,
Schlessinger D,
Schunkert H,
Schwarz P,
Seedorf U,
Selvin E,
Serrano-Ríos M,
Shrader P,
Silveira A,
Siscovick D,
Song K,
Spector TD,
Stefansson K,
Steinthorsdottir V,
Strachan DP,
Strawbridge R,
Stumvoll M,
Surakka I,
Swift AJ,
Tanaka T,
Teumer A,
Thorleifsson G,
Thorsteinsdottir U,
Tönjes A,
Usala G,
Vitart V,
Völzke H,
Wallaschofski H,
Waterworth DM,
Watkins H,
Wichmann HE,
Wild SH,
Willemsen G,
Williams GH,
Wilson JF,
Winkelmann J,
Wright AF,
Zabena C,
Zhao JH,
Epstein SE,
Erdmann J,
Hakonarson HH,
Kathiresan S,
Khaw KT,
Roberts R,
Samani NJ,
Fleming MD,
Sladek R,
Abecasis G,
Boehnke M,
Froguel P,
Groop L,
McCarthy MI,
Kao WH,
Florez JC,
Uda M,
Wareham NJ,
Barroso I,
Meigs JB
Diabetes · 2010 · PMID 20858683 · open access
Questions about rs1799884
What is rs1799884?
rs1799884 is a single position in the genome, in or near the GCK gene. Published research associates it with glycated hemoglobin levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs1799884 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1799884 come from?
GWAS Catalog, Diabetes 2010, PMID:20858683. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants