Sensitive

Chronotype and ER+ breast cancer

TRPS1 · rs179444

Where this position leads

Condition: Breast Cancer

rs179444 Condition: Breast Cancer Breast Cancer Condition rs179444 rs179444 TRPS1

What the study found

Who was studied 449,734 European ancestry individuals, 69,501 European ancestry ER+ breast cancer cases, 105,974 European ancestry controls.

The effect The reported allele is G; the catalogue records no effect size ; p = 1 × 10−14.

Where it sits Chromosome 8, band 8q23.3 — in an intron of TRPS1.

What each result means

G/G Two copies of the version the research linked to Chronotype and ER+ breast cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.
G/T One copy of the version the research linked to Chronotype and ER+ breast cancer. That is a smaller link than two copies.
T/T No copy of the version the research linked to Chronotype and ER+ breast cancer. This is the starting point the study compared everyone against.
Source

Questions about rs179444

What is rs179444?

rs179444 is a single position in the genome, in or near the TRPS1 gene. Published research associates it with chronotype and er+ breast cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs179444 linked to?

On MyGeneLog this position is linked to Breast Cancer. The research behind each link, and its sources, are set out on that condition page.

Does having rs179444 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs179444 come from?

GWAS Catalog, Journal of sleep research 2024, PMID:37380357. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Chronotype and ER+ breast cancer (rs179444). MyGeneLog™. https://www.mygenelog.com/variants/rs179444

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