0 433229123120Reads by AI crawlersClaude3ChatGPT2Google · Gemini0Perplexity2Meta AI9Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others20Total43Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 1,434 Han Chinese ancestry cases, 4,270 Han Chinese ancestry controls; replicated in 2,703 Han Chinese ancestry cases, 3,464 Han Chinese ancestry controls.
The effect
Each copy of the A allele carried 1.30 times the odds of IgA nephropathy (95% confidence interval 1.21-1.39); p = 3 × 10−13.
How common The A allele had a frequency of about 15% in the people studied.
Where it sits Chromosome 6, band 6p21.32 — between genes, 2.7 kb from MTCO3P1.
What each result means
A/ATwo copies of the version the research linked to IgA nephropathy. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to IgA nephropathy. That is a smaller link than two copies.
G/GNo copy of the version the research linked to IgA nephropathy. This is the starting point the study compared everyone against.
rs1794275 is a single position in the genome, in or near the HLA-DQA/B gene. Published research associates it with iga nephropathy. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs1794275 linked to?
On MyGeneLog this position is linked to IgA Nephropathy. The research behind each link, and its sources, are set out on that condition page.
Does having rs1794275 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1794275 come from?
GWAS Catalog, Nat Genet 2011, PMID:22197929. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 433229123120Reads by AI crawlersClaude3ChatGPT2Google · Gemini0Perplexity2Meta AI9Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others20Total43Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
IgA nephropathy (rs1794275). MyGeneLog™. https://www.mygenelog.com/variants/rs1794275