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Matrix metalloproteinase-7 levels

MMP7 · rs17884405

What the study found

Who was studied 21,758 European ancestry individuals; replicated in 9,173 individuals.

The effect Each copy of the T allele shifted the measure 0.14 lower; p = 6 × 10−28.

How common The T allele had a frequency of about 22% in the people studied.

Where it sits Chromosome 11, band 11q22.2 — in an intron of MMP7.

What each result means

C/C No copy of the version the research linked to Matrix metalloproteinase-7 levels. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Matrix metalloproteinase-7 levels. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Matrix metalloproteinase-7 levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs17884405

What is rs17884405?

rs17884405 is a single position in the genome, in or near the MMP7 gene. Published research associates it with matrix metalloproteinase-7 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs17884405 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs17884405 come from?

GWAS Catalog, Nature metabolism 2020, PMID:33067605. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Matrix metalloproteinase-7 levels (rs17884405). MyGeneLog™. https://www.mygenelog.com/variants/rs17884405

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