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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 21,758 European ancestry individuals; replicated in 9,173 individuals.
The effect
Each copy of the T allele shifted the measure 1.05 higher; p = 5 × 10−155.
How common The T allele had a frequency of about 98% in the people studied.
Where it sits Chromosome 11, band 11q22.2 — inside MMP10.
What ClinVar records
ClassificationBenign for Ovarian serous cystadenocarcinoma, Malignant tumor of esophagus, Cervical cancer, Cholangiocarcinoma, Lung cancer and 4 more; criteria provided, single submitter (1 of 4 stars, 2 submitters), last evaluated 2023-02-01.
ClinVar record 2642323NM_002425.3(MMP10):c.497-2A>G
What this is ClinVar's aggregate record for this position (as of its 2026-10-12 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.
What each result means
C/CNo copy of the version the research linked to Matrix metalloproteinase-10 levels. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Matrix metalloproteinase-10 levels. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Matrix metalloproteinase-10 levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs17860955 is a single position in the genome, in or near the MMP10 gene. Published research associates it with matrix metalloproteinase-10 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs17860955 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs17860955 come from?
GWAS Catalog, Nature metabolism 2020, PMID:33067605. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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