Standard

Biological Sibling: Asthma

near HLA-DQA1 · rs17843606

Where this position leads

Condition: Asthma

rs17843606 Condition: Asthma Asthma Condition rs17843606 rs17843606 near HLA-DQA1

What the study found

Who was studied 5,022 African American or Afro-Caribbean cases, 50,483 African American or Afro-Caribbean controls, 2,302 Hispanic or Latin American cases, 27,012 Hispanic or Latin American controls, 313 East Asian ancestry cases, 3,234 East Asian ancestry controls, 18,209 European ancestry cases, 297,459 European ancestry controls.

The effect Each copy of the G allele shifted the measure 0.0804 lower (95% confidence interval 0.062-0.099); p = 3 × 10−15.

How common The G allele had a frequency of about 41% in the people studied.

Where it sits Chromosome 6, band 6p21.32 — between genes, 5.6 kb from HLA-DQA1.

What each result means

G/G Two copies of the version the research linked to Biological Sibling: Asthma. That is the strongest link of the three results. A link in a study is not a diagnosis.
G/T One copy of the version the research linked to Biological Sibling: Asthma. That is a smaller link than two copies.
T/T No copy of the version the research linked to Biological Sibling: Asthma. This is the starting point the study compared everyone against.
Source

Questions about rs17843606

What is rs17843606?

rs17843606 is a single position in the genome, in or near the near HLA-DQA1 gene. Published research associates it with biological sibling: asthma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs17843606 linked to?

On MyGeneLog this position is linked to Asthma. The research behind each link, and its sources, are set out on that condition page.

Does having rs17843606 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs17843606 come from?

GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Biological Sibling: Asthma (rs17843606). MyGeneLog™. https://www.mygenelog.com/variants/rs17843606

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