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Bipolar disorder

ADCY2 · rs17826816

Where this position leads

Condition: Bipolar Disorder

rs17826816 Condition: Bipolar Disorder Bipolar Disorder Condition rs17826816 rs17826816 ADCY2

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Bipolar disorder — no copies of the reported risk allele.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Bipolar disorder.
G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Bipolar disorder compared to the general population.
Source
Genome-wide association study reveals two new risk loci for bipolar disorder
Mühleisen TW, Leber M, Schulze TG, Strohmaier J, Degenhardt F, Treutlein J, Mattheisen M, Forstner AJ, Schumacher J, Breuer R, Meier S, Herms S
and 51 more — show all
Hoffmann P, Lacour A, Witt SH, Reif A, Müller-Myhsok B, Lucae S, Maier W, Schwarz M, Vedder H, Kammerer-Ciernioch J, Pfennig A, Bauer M, Hautzinger M, Moebus S, Priebe L, Czerski PM, Hauser J, Lissowska J, Szeszenia-Dabrowska N, Brennan P, McKay JD, Wright A, Mitchell PB, Fullerton JM, Schofield PR, Montgomery GW, Medland SE, Gordon SD, Martin NG, Krasnow V, Chuchalin A, Babadjanova G, Pantelejeva G, Abramova LI, Tiganov AS, Polonikov A, Khusnutdinova E, Alda M, Grof P, Rouleau GA, Turecki G, Laprise C, Rivas F, Mayoral F, Kogevinas M, Grigoroiu-Serbanescu M, Propping P, Becker T, Rietschel M, Nöthen MM, Cichon S
Nature communications · 2014 · PMID 24618891

Questions about rs17826816

What is rs17826816?

rs17826816 is a single position in the genome, in or near the ADCY2 gene. Published research associates it with bipolar disorder. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs17826816 linked to?

On MyGeneLog this position is linked to Bipolar Disorder. The research behind each link, and its sources, are set out on that condition page.

Does having rs17826816 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs17826816 come from?

GWAS Catalog, Nat Commun 2014, PMID:24618891. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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