SPPL2C · rs17769552
Where this position leads
Condition: Hand Grip Strength
What the study found
Who was studied 334,825 British ancestry individuals.
The effect Each copy of the A allele shifted the measure 0.002 lower (95% confidence interval 0.0014-0.0026); p = 2 × 10−8.
How common The A allele had a frequency of about 22% in the people studied.
Where it sits Chromosome 17, band 17q21.31 — in an intron of MAPT-AS1.
rs17769552 is a single position in the genome, in or near the SPPL2C gene. Published research associates it with hand grip strength. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
On MyGeneLog this position is linked to Hand Grip Strength. The research behind each link, and its sources, are set out on that condition page.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Sci Rep 2018, PMID:29691431. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Hand grip strength (rs17769552). MyGeneLog™. https://www.mygenelog.com/variants/rs17769552