Standard
Ankylosing spondylitis
BACH2 · rs17765610
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
A/A
Published research associates this genotype with typical/baseline likelihood of Ankylosing spondylitis — no copies of the reported risk allele.
A/G
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Ankylosing spondylitis.
G/G
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Ankylosing spondylitis compared to the general population.
Source
Identification of multiple risk variants for ankylosing spondylitis through high-density genotyping of immune-related loci
Cortes A,
Hadler J,
Pointon JP,
Robinson PC,
Karaderi T,
Leo P,
Cremin K,
Pryce K,
Harris J,
Lee S,
Joo KB,
Shim SC
and 53 more — show all
Weisman M,
Ward M,
Zhou X,
Garchon HJ,
Chiocchia G,
Nossent J,
Lie BA,
Førre Ø,
Tuomilehto J,
Laiho K,
Jiang L,
Liu Y,
Wu X,
Bradbury LA,
Elewaut D,
Burgos-Vargas R,
Stebbings S,
Appleton L,
Farrah C,
Lau J,
Kenna TJ,
Haroon N,
Ferreira MA,
Yang J,
Mulero J,
Fernandez-Sueiro JL,
Gonzalez-Gay MA,
Lopez-Larrea C,
Deloukas P,
Donnelly P,
Bowness P,
Gafney K,
Gaston H,
Gladman DD,
Rahman P,
Maksymowych WP,
Xu H,
Crusius JB,
van der Horst-Bruinsma IE,
Chou CT,
Valle-Oñate R,
Romero-Sánchez C,
Hansen IM,
Pimentel-Santos FM,
Inman RD,
Videm V,
Martin J,
Breban M,
Reveille JD,
Evans DM,
Kim TH,
Wordsworth BP,
Brown MA
Nature genetics · 2013 · PMID 23749187
Questions about rs17765610
What is rs17765610?
rs17765610 is a single position in the genome, in or near the BACH2 gene. Published research associates it with ankylosing spondylitis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs17765610 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs17765610 come from?
GWAS Catalog, Nat Genet 2013, PMID:23749187. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants