Monounsaturated fatty acids to total fatty acids percentage
MACF1 · rs1775654
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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 98,316 European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.0476 higher (95% confidence interval 0.033-0.062); p = 4 × 10−11.
How common The T allele had a frequency of about 26% in the people studied.
Where it sits Chromosome 1, band 1p34.3 — in an intron of MACF1.
What each result means
C/CPublished research associates this genotype with typical/baseline likelihood of Monounsaturated fatty acids to total fatty acids percentage — no copies of the reported risk allele.
C/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Monounsaturated fatty acids to total fatty acids percentage.
T/TPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Monounsaturated fatty acids to total fatty acids percentage compared to the general population.
Ophthalmology science · 2024 · PMID 39091897 · open access
Questions about rs1775654
What is rs1775654?
rs1775654 is a single position in the genome, in or near the MACF1 gene. Published research associates it with monounsaturated fatty acids to total fatty acids percentage. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs1775654 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1775654 come from?
GWAS Catalog, Ophthalmology science 2024, PMID:39091897. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Monounsaturated fatty acids to total fatty acids percentage (rs1775654). MyGeneLog™. https://www.mygenelog.com/variants/rs1775654