Standard

Mean corpuscular volume

AFF1 · rs17752307

Where this position leads

Condition: Blood Cell Counts

rs17752307 Condition: Blood Cell Counts Blood Cell Counts Condition rs17752307 rs17752307 AFF1

What the study found

Who was studied 350,473 European ancestry individuals, 129,832 East Asian ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0329 lower (95% confidence interval 0.028-0.037); p = 2 × 10−44.

Where it sits Chromosome 4, band 4q21.3 — in an intron of AFF1.

What each result means

G/G Two copies of the version the research linked to Mean corpuscular volume. That is the strongest link of the three results. A link in a study is not a diagnosis.
G/T One copy of the version the research linked to Mean corpuscular volume. That is a smaller link than two copies.
T/T No copy of the version the research linked to Mean corpuscular volume. This is the starting point the study compared everyone against.
Source

Questions about rs17752307

What is rs17752307?

rs17752307 is a single position in the genome, in or near the AFF1 gene. Published research associates it with mean corpuscular volume. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs17752307 linked to?

On MyGeneLog this position is linked to Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.

Does having rs17752307 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs17752307 come from?

GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Mean corpuscular volume (rs17752307). MyGeneLog™. https://www.mygenelog.com/variants/rs17752307

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