Standard

Diacylglycerol (12:0/18:0) (Model 2)

near TNKS · rs17729883

What the study found

Who was studied 6,725 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.139 lower; p = 2 × 10−15.

Where it sits Chromosome 8, band 8p23.1 — in an intron of PPP1R3B-DT.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Diacylglycerol (12:0/18:0) (Model 2) — no copies of the reported risk allele.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Diacylglycerol (12:0/18:0) (Model 2).
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Diacylglycerol (12:0/18:0) (Model 2) compared to the general population.
Source

Questions about rs17729883

What is rs17729883?

rs17729883 is a single position in the genome, in or near the near TNKS gene. Published research associates it with diacylglycerol (12:0/18:0) (model 2). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs17729883 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs17729883 come from?

GWAS Catalog, Nature communications 2026, PMID:42069741. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Diacylglycerol (12:0/18:0) (Model 2) (rs17729883). MyGeneLog™. https://www.mygenelog.com/variants/rs17729883

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