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Hip shape (DXA scan)

IRX1 · rs17725170

What the study found

Who was studied 10,217 European ancestry individuals, 5,717 individuals.

The effect Each copy of the A allele shifted the measure 0.079 lower (95% confidence interval 0.046-0.112); p = 6 × 10−9.

How common The A allele had a frequency of about 25% in the people studied.

Where it sits Chromosome 5, band 5p15.33 — between genes, 145.3 kb from LINC02063.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Hip shape (DXA scan) compared to the general population.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Hip shape (DXA scan).
G/G Published research associates this genotype with typical/baseline likelihood of Hip shape (DXA scan) — no copies of the reported risk allele.
Source

Questions about rs17725170

What is rs17725170?

rs17725170 is a single position in the genome, in or near the IRX1 gene. Published research associates it with hip shape (dxa scan). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs17725170 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs17725170 come from?

GWAS Catalog, J Bone Miner Res 2018, PMID:30320955. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Hip shape (DXA scan) (rs17725170). MyGeneLog™. https://www.mygenelog.com/variants/rs17725170

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