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Who was studied 86 European ancestry whole-genome sequenced cases, 4,280 European ancestry cases, 13,941 European ancestry whole-genome sequenced controls, 700,740 European ancestry controls.
The effect
Each copy of the C allele carried 1.18 times the odds of Nasal polyps (95% confidence interval 1.12-1.23); p = 1 × 10−11.
How common The C allele had a frequency of about 70% in the people studied.
Where it sits Chromosome 3, band 3p13 — in an intron of FOXP1.
What each result means
C/CTwo copies of the version the research linked to Nasal polyps. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Nasal polyps. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Nasal polyps. This is the starting point the study compared everyone against.
rs17718444 is a single position in the genome, in or near the FOXP1 gene. Published research associates it with nasal polyps. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs17718444 linked to?
On MyGeneLog this position is linked to Chronic Rhinosinusitis and the Bitter Taste Receptor. The research behind each link, and its sources, are set out on that condition page.
Does having rs17718444 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs17718444 come from?
GWAS Catalog, Nat Genet 2019, PMID:30643255. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
2 282422216Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity2Meta AI4Microsoft · Copilot0Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others16Total28Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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