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Blood urea nitrogen levels

SH3YL1 · rs17713396

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What the study found

Who was studied 679,531 European ancestry individuals, 173,149 individuals.

The effect Each copy of the T allele shifted the measure 0.0048 higher (95% confidence interval 0.0038-0.0058); p = 3 × 10⁻²¹.

How common The T allele had a frequency of about 33% in the people studied.

Where it sits Chromosome 2, band 2p25.3 — in an intron of SH3YL1.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Blood urea nitrogen levels — no copies of the reported risk allele.

C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Blood urea nitrogen levels.

T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Blood urea nitrogen levels compared to the general population.

Source

Discovery and prioritization of variants and genes for kidney function in >1.2 million individuals

Stanzick KJ, Li Y, Schlosser P, Gorski M, Wuttke M, Thomas LF, Rasheed H, Rowan BX, Graham SE, Vanderweff BR, Patil SB, Robinson-Cohen C

and 12 more — show all

Gaziano JM, O'Donnell CJ, Willer CJ, Hallan S, Åsvold BO, Gessner A, Hung AM, Pattaro C, Köttgen A, Stark KJ, Heid IM, Winkler TW

VA Million Veteran Program

Nature communications · 2021 · PMID 34272381 · open access

Questions about rs17713396

What is rs17713396?

rs17713396 is a single position in the genome, in or near the SH3YL1 gene. Published research associates it with blood urea nitrogen levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs17713396 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs17713396 come from?

GWAS Catalog, Nature communications 2021, PMID:34272381. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Blood urea nitrogen levels (rs17713396). MyGeneLog™. https://www.mygenelog.com/variants/rs17713396

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