Sensitive

Type 1 diabetes

C12orf30 · rs17696736

Where this position leads

Condition: Type 1 Diabetes

rs17696736 Condition: Type 1 Diabetes Type 1 Diabetes Condition rs17696736 rs17696736 C12orf30

What the study found

Who was studied 2,000 European ancestry cases, 3,000 European ancestry controls; replicated in 2,997 European ancestry trios, 4,000 European ancestry cases, 5,000 European ancestry controls.

The effect Each copy of the G allele carried 1.22 times the odds of Type 1 diabetes (95% confidence interval 1.15-1.28); p = 2 × 10−16.

How common The G allele had a frequency of about 42% in the people studied.

Where it sits Chromosome 12, band 12q24.13 — in an intron of NAA25.

What each result means

A/A No copy of the version the research linked to Type 1 diabetes. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Type 1 diabetes. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Type 1 diabetes. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs17696736

What is rs17696736?

rs17696736 is a single position in the genome, in or near the C12orf30 gene. Published research associates it with type 1 diabetes. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs17696736 linked to?

On MyGeneLog this position is linked to Type 1 Diabetes. The research behind each link, and its sources, are set out on that condition page.

Does having rs17696736 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs17696736 come from?

GWAS Catalog, Nat Genet 2007, PMID:17554260. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Type 1 diabetes (rs17696736). MyGeneLog™. https://www.mygenelog.com/variants/rs17696736

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