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Cardiorespiratory fitness

SVIL-AS1 · rs17695155

What the study found

Who was studied 69,416 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.2 higher (95% confidence interval 0.12-0.28); p = 1 × 10−8.

Where it sits Chromosome 10, band 10p11.23 — in an intron of SVIL-AS1.

What ClinVar records

Classification Benign; criteria provided, multiple submitters, no conflicts (2 of 4 stars, 2 submitters), last evaluated 2021-05-15. ClinVar record 1281768 NM_021738.3(SVIL):c.2009+173A>G

What this is ClinVar's aggregate record for this position (as of its 2026-10-12 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.

What each result means

C/C No copy of the version the research linked to Cardiorespiratory fitness. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Cardiorespiratory fitness. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Cardiorespiratory fitness. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs17695155

What is rs17695155?

rs17695155 is a single position in the genome, in or near the SVIL-AS1 gene. Published research associates it with cardiorespiratory fitness. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs17695155 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs17695155 come from?

GWAS Catalog, Nature communications 2023, PMID:37400433. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Cardiorespiratory fitness (rs17695155). MyGeneLog™. https://www.mygenelog.com/variants/rs17695155

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