Standard

Atopic march

IL4 · rs17690965

What the study found

Who was studied 1,151 European ancestry early-onset eczema and childhood asthma cases, 10,030 European ancestry controls; replicated in 1,277 European ancestry early-onset eczema and childhood asthma cases, 7,004 European ancestry controls.

The effect Each copy of the C allele carried 1.24 times the odds of Atopic march (95% confidence interval 1.15-1.33); p = 5 × 10−8.

How common The C allele had a frequency of about 26% in the people studied.

Where it sits Chromosome 5, band 5q31.1 — in the 3′ untranslated region of KIF3A.

What each result means

C/C Two copies of the version the research linked to Atopic march. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/G One copy of the version the research linked to Atopic march. That is a smaller link than two copies.
G/G No copy of the version the research linked to Atopic march. This is the starting point the study compared everyone against.
Source

Questions about rs17690965

What is rs17690965?

rs17690965 is a single position in the genome, in or near the IL4 gene. Published research associates it with atopic march. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs17690965 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs17690965 come from?

GWAS Catalog, Nat Commun 2015, PMID:26542096. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Atopic march (rs17690965). MyGeneLog™. https://www.mygenelog.com/variants/rs17690965

← See all variants