Sensitive

Major depressive disorder or hospitalized COVID-19 (pleiotropy)

LINC02210-CRHR1 · rs17689471

Where this position leads

Condition: Major Depressive Disorder

rs17689471 Condition: Major Depressive Disorder Major Depressive Disorder Condition rs17689471 rs17689471 LINC02210-CR…

What the study found

Who was studied 65,075 European ancestry MDD cases, 24,274 European ancestry hospitalized COVID-19 cases, 2,294,081 European ancestry controls.

The effect The reported allele is C; the catalogue records no effect size ; p = 1 × 10−12.

Where it sits Chromosome 17, band 17q21.31 — in an intron of LINC02210-CRHR1.

What each result means

C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Major depressive disorder or hospitalized COVID-19 (pleiotropy) compared to the general population.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Major depressive disorder or hospitalized COVID-19 (pleiotropy).
T/T Published research associates this genotype with typical/baseline likelihood of Major depressive disorder or hospitalized COVID-19 (pleiotropy) — no copies of the reported risk allele.
Source

Questions about rs17689471

What is rs17689471?

rs17689471 is a single position in the genome, in or near the LINC02210-CRHR1 gene. Published research associates it with major depressive disorder or hospitalized covid-19 (pleiotropy). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs17689471 linked to?

On MyGeneLog this position is linked to Major Depressive Disorder. The research behind each link, and its sources, are set out on that condition page.

Does having rs17689471 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs17689471 come from?

GWAS Catalog, Frontiers in psychiatry 2023, PMID:37426090. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Major depressive disorder or hospitalized COVID-19 (pleiotropy) (rs17689471). MyGeneLog™. https://www.mygenelog.com/variants/rs17689471

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