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Who was studied 250 Korean ancestry cases, 296 Korean ancestry controls.
The effect
Each copy of the G allele carried 3.70 times the odds of Intracranial aneurysm (95% confidence interval 2.63-5.26); p = 6 × 10−13.
How common The G allele had a frequency of about 67% in the people studied.
Where it sits Chromosome 4, band 4q34.2 — between genes, 82 kb from HAFML.
What each result means
A/ANo copy of the version the research linked to Intracranial aneurysm. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Intracranial aneurysm. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Intracranial aneurysm. That is the strongest link of the three results. A link in a study is not a diagnosis.
Journal of clinical medicine · 2019 · PMID 30823506 · open access
Questions about rs17688188
What is rs17688188?
rs17688188 is a single position in the genome, in or near the SPCS3 gene. Published research associates it with intracranial aneurysm. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs17688188 linked to?
On MyGeneLog this position is linked to Intracranial Aneurysm. The research behind each link, and its sources, are set out on that condition page.
Does having rs17688188 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs17688188 come from?
GWAS Catalog, Journal of clinical medicine 2019, PMID:30823506. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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