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Systolic blood pressure

BRAP · rs17685230

Where this position leads

Condition: Blood Pressure

rs17685230 Condition: Blood Pressure Blood Pressure Condition rs17685230 rs17685230 BRAP

What the study found

Who was studied 526,001 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.872 lower (95% confidence interval 0.64-1.1); p = 6 × 10−14.

Where it sits Chromosome 12, band 12q24.12 — in an intron of BRAP.

What each result means

A/A Two copies of the version the research linked to Systolic blood pressure. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Systolic blood pressure. That is a smaller link than two copies.
G/G No copy of the version the research linked to Systolic blood pressure. This is the starting point the study compared everyone against.
Source

Questions about rs17685230

What is rs17685230?

rs17685230 is a single position in the genome, in or near the BRAP gene. Published research associates it with systolic blood pressure. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs17685230 linked to?

On MyGeneLog this position is linked to Blood Pressure. The research behind each link, and its sources, are set out on that condition page.

Does having rs17685230 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs17685230 come from?

GWAS Catalog, Investigative ophthalmology & visual science 2022, PMID:35762941. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Systolic blood pressure (rs17685230). MyGeneLog™. https://www.mygenelog.com/variants/rs17685230

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