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Leg fat percentage right (UKB data field 23111)

ZBTB20 · rs17685222

What the study found

Who was studied 394,642 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0154 lower (95% confidence interval 0.011-0.02); p = 1 × 10−12.

How common The T allele had a frequency of about 8% in the people studied.

Where it sits Chromosome 3, band 3q13.31 — in an intron of ZBTB20.

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Leg fat percentage right (UKB data field 23111) — no copies of the reported risk allele.
A/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Leg fat percentage right (UKB data field 23111).
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Leg fat percentage right (UKB data field 23111) compared to the general population.
Source

Questions about rs17685222

What is rs17685222?

rs17685222 is a single position in the genome, in or near the ZBTB20 gene. Published research associates it with leg fat percentage right (ukb data field 23111). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs17685222 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs17685222 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Leg fat percentage right (UKB data field 23111) (rs17685222). MyGeneLog™. https://www.mygenelog.com/variants/rs17685222

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