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Educational attainment

near LDHBP3 · rs17669337

Where this position leads

Condition: Educational Attainment

rs17669337 Condition: Educational Attainment Educational Attainment Condition rs17669337 rs17669337 near LDHBP3

What the study found

Who was studied 3,037,499 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0101 lower (95% confidence interval 0.008-0.0122); p = 2 × 10−21.

How common The T allele had a frequency of about 41% in the people studied.

Where it sits Chromosome 5, band 5q14.3 — between genes, 10.6 kb from LDHBP3.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Educational attainment — no copies of the reported risk allele.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Educational attainment.
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Educational attainment compared to the general population.
Source
Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals
Okbay A, Wu Y, Wang N, Jayashankar H, Bennett M, Nehzati SM, Sidorenko J, Kweon H, Goldman G, Gjorgjieva T, Jiang Y, Hicks B
and 26 more — show all
Tian C, Hinds DA, Ahlskog R, Magnusson PKE, Oskarsson S, Hayward C, Campbell A, Porteous DJ, Freese J, Herd P, Watson C, Jala J, Conley D, Koellinger PD, Johannesson M, Laibson D, Meyer MN, Lee JJ, Kong A, Yengo L, Cesarini D, Turley P, Visscher PM, Beauchamp JP, Benjamin DJ, Young AI
23andMe Research Team · Social Science Genetic Association Consortium
Nature genetics · 2022 · PMID 35361970 · open access

Questions about rs17669337

What is rs17669337?

rs17669337 is a single position in the genome, in or near the near LDHBP3 gene. Published research associates it with educational attainment. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs17669337 linked to?

On MyGeneLog this position is linked to Educational Attainment. The research behind each link, and its sources, are set out on that condition page.

Does having rs17669337 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs17669337 come from?

GWAS Catalog, Nature genetics 2022, PMID:35361970. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Educational attainment (rs17669337). MyGeneLog™. https://www.mygenelog.com/variants/rs17669337

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