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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 340,860 European ancestry individuals, 5,962 African ancestry individuals, 7,275 South Asian ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.0224 higher (95% confidence interval 0.016-0.029); p = 2 × 10−11.
Where it sits Chromosome 2, band 2p24.1 — a missense change in LDAH.
What each result means
A/ATwo copies of the version the research linked to Apolipoprotein B levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/COne copy of the version the research linked to Apolipoprotein B levels. That is a smaller link than two copies.
C/CNo copy of the version the research linked to Apolipoprotein B levels. This is the starting point the study compared everyone against.
Nature genetics · 2021 · PMID 33462484 · open access
Questions about rs17663874
What is rs17663874?
rs17663874 is a single position in the genome, in or near the LDAH gene. Published research associates it with apolipoprotein b levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs17663874 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs17663874 come from?
GWAS Catalog, Nature genetics 2021, PMID:33462484. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Apolipoprotein B levels (rs17663874). MyGeneLog™. https://www.mygenelog.com/variants/rs17663874