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Anti-varicella zoster virus IgG seropositivity

HLA-DQB1 · rs1766

What the study found

Who was studied 8,735 White British ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.04 lower; p = 1 × 10−11.

How common The A allele had a frequency of about 53% in the people studied.

Where it sits Chromosome 6, band 6p21.32 — in the 3′ untranslated region of HLA-DQB1.

What each result means

A/A Two copies of the version the research linked to Anti-varicella zoster virus IgG seropositivity. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Anti-varicella zoster virus IgG seropositivity. That is a smaller link than two copies.
G/G No copy of the version the research linked to Anti-varicella zoster virus IgG seropositivity. This is the starting point the study compared everyone against.
Source

Questions about rs1766

What is rs1766?

rs1766 is a single position in the genome, in or near the HLA-DQB1 gene. Published research associates it with anti-varicella zoster virus igg seropositivity. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs1766 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1766 come from?

GWAS Catalog, Open forum infectious diseases 2020, PMID:33204752. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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Anti-varicella zoster virus IgG seropositivity (rs1766). MyGeneLog™. https://www.mygenelog.com/variants/rs1766

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