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Who was studied 39,427 European ancestry cases, 378,169 European ancestry controls.
The effect
Each copy of the A allele carried 1.06 times the odds of Osteoarthritis of the hip or knee (95% confidence interval 1.04-1.07); p = 2 × 10−10.
How common The A allele had a frequency of about 71% in the people studied.
Where it sits Chromosome 11, band 11p14.1 — in an intron of LINC02742.
What each result means
A/ATwo copies of the version the research linked to Osteoarthritis of the hip or knee. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/COne copy of the version the research linked to Osteoarthritis of the hip or knee. That is a smaller link than two copies.
C/CNo copy of the version the research linked to Osteoarthritis of the hip or knee. This is the starting point the study compared everyone against.
Nature genetics · 2019 · PMID 30664745 · open access
Questions about rs17659798
What is rs17659798?
rs17659798 is a single position in the genome, in or near the LINC02742 gene. Published research associates it with osteoarthritis of the hip or knee. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs17659798 linked to?
On MyGeneLog this position is linked to Osteoarthritis. The research behind each link, and its sources, are set out on that condition page.
Does having rs17659798 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs17659798 come from?
GWAS Catalog, Nature genetics 2019, PMID:30664745. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Osteoarthritis of the hip or knee (rs17659798). MyGeneLog™. https://www.mygenelog.com/variants/rs17659798