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Serum levels of protein NFKB1

near IGKV6D-41 · rs17620337

What the study found

Who was studied 5,365 Icelandic ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.435 lower (95% confidence interval 0.37-0.5); p = 3 × 10−38.

How common The T allele had a frequency of about 8% in the people studied.

Where it sits Chromosome 2, band 2p11.2 — between genes, 3.7 kb from IGKV6D-41.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Serum levels of protein NFKB1 — no copies of the reported risk allele.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Serum levels of protein NFKB1.
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Serum levels of protein NFKB1 compared to the general population.
Source

Questions about rs17620337

What is rs17620337?

rs17620337 is a single position in the genome, in or near the near IGKV6D-41 gene. Published research associates it with serum levels of protein nfkb1. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs17620337 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs17620337 come from?

GWAS Catalog, Nature communications 2022, PMID:35078996. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Serum levels of protein NFKB1 (rs17620337). MyGeneLog™. https://www.mygenelog.com/variants/rs17620337

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