Sensitive

Schizophrenia

BMPR1B · rs17616243

Where this position leads

Condition: Schizophrenia

rs17616243 Condition: Schizophrenia Schizophrenia Condition rs17616243 rs17616243 BMPR1B

What the study found

Who was studied 924 Greek ancestry cases, 1,125 Greek ancestry controls.

The effect Each copy of the T allele carried 2.03 times the odds of Schizophrenia (95% confidence interval 1.79-2.27); p = 3 × 10−9.

How common The T allele had a frequency of about 16% in the people studied.

Where it sits Chromosome 4, band 4q22.3 — in an intron of BMPR1B.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Schizophrenia — no copies of the reported risk allele.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Schizophrenia.
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Schizophrenia compared to the general population.
Source

Questions about rs17616243

What is rs17616243?

rs17616243 is a single position in the genome, in or near the BMPR1B gene. Published research associates it with schizophrenia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs17616243 linked to?

On MyGeneLog this position is linked to Schizophrenia. The research behind each link, and its sources, are set out on that condition page.

Does having rs17616243 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs17616243 come from?

GWAS Catalog, Transl Psychiatry 2018, PMID:30470734. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Schizophrenia (rs17616243). MyGeneLog™. https://www.mygenelog.com/variants/rs17616243

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