Standard

QRS duration

GOSR2 · rs17608766

Where this position leads

Condition: Cardiac Conduction Intervals (PR Interval and QRS Duration)

rs17608766 Condition: Cardiac Conduction Intervals (PR Interval and QRS Duration) Cardiac Conduction Intervals (PR In… Condition Topic: Heart and circulation Heart and circulation Topic rs17608766 rs17608766 GOSR2

Solid lines are connections this site curates. Dashed lines mean the two ends share a research paper — worth knowing, and not a claim that one explains the other.

What the study found

Who was studied 39,717 European ancestry individuals, 690 Orcadian individuals; replicated in 7,170 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.53 ms higher (95% confidence interval 0.33-0.73); p = 5 × 10−10.

How common The C allele had a frequency of about 16% in the people studied.

Where it sits Chromosome 17, band 17q21.32 — in the 3′ untranslated region of LRRC37A2.

What each result means

C/C Two copies of the version the research linked to QRS duration. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to QRS duration. That is a smaller link than two copies.
T/T No copy of the version the research linked to QRS duration. This is the starting point the study compared everyone against.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs17608766

What is rs17608766?

rs17608766 is a single position in the genome, in or near the GOSR2 gene. Published research associates it with qrs duration. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs17608766 linked to?

On MyGeneLog this position is linked to Cardiac Conduction Intervals (PR Interval and QRS Duration). The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs17608766?

Subjects that appear in the title or abstract of the same papers as this rsID include heart and circulation (5 papers), blood sugar and insulin (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs17608766 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs17608766 come from?

GWAS Catalog, Nat Genet 2010, PMID:21076409. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

QRS duration (rs17608766). MyGeneLog™. https://www.mygenelog.com/variants/rs17608766

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