Sensitive

Response to radiotherapy in prostate cancer (toxicity, urinary frequency)

FAM53C · rs17599026

Where this position leads

Condition: Prostate Cancer

rs17599026 Condition: Prostate Cancer Prostate Cancer Condition rs17599026 rs17599026 FAM53C

What the study found

Who was studied 1,409 European ancestry individuals.

The effect Each copy of the T allele carried 3.12 times the odds of Response to radiotherapy in prostate cancer (toxicity, urinary frequency) (95% confidence interval 2.08-4.69); p = 4 × 10−8.

How common The T allele had a frequency of about 8% in the people studied.

Where it sits Chromosome 5, band 5q31.2 — in an intron of KDM3B.

What each result means

C/C No copy of the version the research linked to Response to radiotherapy in prostate cancer (toxicity, urinary frequency). This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Response to radiotherapy in prostate cancer (toxicity, urinary frequency). That is a smaller link than two copies.
T/T Two copies of the version the research linked to Response to radiotherapy in prostate cancer (toxicity, urinary frequency). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs17599026

What is rs17599026?

rs17599026 is a single position in the genome, in or near the FAM53C gene. Published research associates it with response to radiotherapy in prostate cancer (toxicity, urinary frequency). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs17599026 linked to?

On MyGeneLog this position is linked to Prostate Cancer. The research behind each link, and its sources, are set out on that condition page.

Does having rs17599026 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs17599026 come from?

GWAS Catalog, EBioMedicine 2016, PMID:27515689. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Response to radiotherapy in prostate cancer (toxicity, urinary frequency) (rs17599026). MyGeneLog™. https://www.mygenelog.com/variants/rs17599026

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