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Morningness

TCF4 · rs17596722

What the study found

Who was studied 434,835 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.018 lower (95% confidence interval 0.012-0.024); p = 3 × 10−11.

How common The T allele had a frequency of about 20% in the people studied.

Where it sits Chromosome 18, band 18q21.2 — in an intron of TCF4.

What each result means

C/C No copy of the version the research linked to Morningness. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Morningness. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Morningness. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs17596722

What is rs17596722?

rs17596722 is a single position in the genome, in or near the TCF4 gene. Published research associates it with morningness. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs17596722 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs17596722 come from?

GWAS Catalog, Nature genetics 2019, PMID:30804565. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Morningness (rs17596722). MyGeneLog™. https://www.mygenelog.com/variants/rs17596722

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