Standard

Mean corpuscular hemoglobin

XPO7 · rs17581959

Where this position leads

Condition: Blood Cell Counts

rs17581959 Condition: Blood Cell Counts Blood Cell Counts Condition rs17581959 rs17581959 XPO7

What the study found

Who was studied 350,472 European ancestry individuals, 128,028 East Asian ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0462 higher (95% confidence interval 0.041-0.051); p = 2 × 10−80.

Where it sits Chromosome 8, band 8p21.3 — in an intron of XPO7.

What each result means

A/A No copy of the version the research linked to Mean corpuscular hemoglobin. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Mean corpuscular hemoglobin. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Mean corpuscular hemoglobin. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs17581959

What is rs17581959?

rs17581959 is a single position in the genome, in or near the XPO7 gene. Published research associates it with mean corpuscular hemoglobin. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs17581959 linked to?

On MyGeneLog this position is linked to Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.

Does having rs17581959 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs17581959 come from?

GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Mean corpuscular hemoglobin (rs17581959). MyGeneLog™. https://www.mygenelog.com/variants/rs17581959

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