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Who was studied 11,320 European ancestry cases, 47,023 European ancestry controls; replicated in 3,248 European ancestry cases, 197,724 European ancestry controls.
The effect
Each copy of the A allele shifted the measure 0.189 lower (95% confidence interval 0.14-0.23); p = 4 × 10−16.
Where it sits Chromosome 22, band 22q13.31 — in an intron of ATXN10.
What each result means
A/ATwo copies of the version the research linked to Dupuytren's disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Dupuytren's disease. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Dupuytren's disease. This is the starting point the study compared everyone against.
Nature communications · 2024 · PMID 38172110 · open access
Questions about rs17573837
What is rs17573837?
rs17573837 is a single position in the genome, in or near the ATXN10 gene. Published research associates it with dupuytren's disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs17573837 linked to?
On MyGeneLog this position is linked to Dupuytren's Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs17573837 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs17573837 come from?
GWAS Catalog, Nature communications 2024, PMID:38172110. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 422Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others2Total4Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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