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Who was studied 8,197 European ancestry cases, 241,468 European ancestry controls; replicated in 1,777 European ancestry cases, 6,088 European ancestry controls.
The effect
Each copy of the C allele carried 1.12 times the odds of Multiple myeloma (95% confidence interval -); p = 9 × 10−9.
How common The C allele had a frequency of about 74% in the people studied.
Where it sits Chromosome 7, band 7q22.3 — between genes, 3.7 kb from CCDC71L.
What each result means
C/CTwo copies of the version the research linked to Multiple myeloma. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Multiple myeloma. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Multiple myeloma. This is the starting point the study compared everyone against.
Nature communications · 2018 · PMID 30213928 · open access
Questions about rs17507636
What is rs17507636?
rs17507636 is a single position in the genome, in or near the near CCDC71L gene. Published research associates it with multiple myeloma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs17507636 linked to?
On MyGeneLog this position is linked to Multiple Myeloma. The research behind each link, and its sources, are set out on that condition page.
Does having rs17507636 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs17507636 come from?
GWAS Catalog, Nat Commun 2018, PMID:30213928. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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