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Retinal thickness (pixel 60_157)

near NEDD9 · rs17507554

What the study found

Who was studied 43,148 European ancestry individuals; replicated in 1,179 Central or South Asian individuals, 1,161 African ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.795 higher (95% confidence interval 0.65-0.94); p = 1 × 10−25.

How common The A allele had a frequency of about 5% in the people studied.

Where it sits Chromosome 6, band 6p24.2 — between genes, 11.7 kb from NEDD9.

What each result means

A/A Two copies of the version the research linked to Retinal thickness (pixel 60_157). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Retinal thickness (pixel 60_157). That is a smaller link than two copies.
G/G No copy of the version the research linked to Retinal thickness (pixel 60_157). This is the starting point the study compared everyone against.
Source

Questions about rs17507554

What is rs17507554?

rs17507554 is a single position in the genome, in or near the near NEDD9 gene. Published research associates it with retinal thickness (pixel 60_157). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs17507554 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs17507554 come from?

GWAS Catalog, Nature communications 2025, PMID:39904976. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Retinal thickness (pixel 60_157) (rs17507554). MyGeneLog™. https://www.mygenelog.com/variants/rs17507554

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