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Triglyceride levels

LPL · rs17489268

What the study found

Who was studied up to 33,431 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 7.78 lower (95% confidence interval 6.66-8.89); p = 2 × 10−42.

How common The A allele had a frequency of about 29% in the people studied.

Where it sits Chromosome 8, band 8p21.3 — between genes, 27.3 kb from LPL.

What each result means

A/A Two copies of the version the research linked to Triglyceride levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/T One copy of the version the research linked to Triglyceride levels. That is a smaller link than two copies.
T/T No copy of the version the research linked to Triglyceride levels. This is the starting point the study compared everyone against.
Source

Questions about rs17489268

What is rs17489268?

rs17489268 is a single position in the genome, in or near the LPL gene. Published research associates it with triglyceride levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs17489268 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs17489268 come from?

GWAS Catalog, Aging (Albany NY) 2018, PMID:29615537. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Triglyceride levels (rs17489268). MyGeneLog™. https://www.mygenelog.com/variants/rs17489268

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