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Polyunsaturated fatty acids to monounsaturated fatty acids ratio

CSGALNACT1 · rs17481744

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

Strength of the evidence

1 / 4

Its strongest genetic-study result is p = 10−9, with 1 associations in the GWAS Catalog.

How this is scored

4: ClinVar disease-causing, reviewed by an expert panel or a guideline (3–4 stars). 3: ClinVar, several labs agreeing (2 stars), or a genetic study at p ≤ 10−50. 2: ClinVar from one lab (1 star), or p ≤ 10−20. 1: ClinVar submitted without criteria (0 stars), or genome-wide significance (p ≤ 5×10−8). The higher of the two counts. It says how solid the evidence is, not whether it matters for a particular person.

What the study found

Who was studied 110,346 European ancestry males.

The effect The reported allele is T; the catalogue records no effect size ; p = 7 × 10−10.

Where it sits Chromosome 8, band 8p21.3 — in an intron of CSGALNACT1.

What each result means

G/G No copy of the version the research linked to Polyunsaturated fatty acids to monounsaturated fatty acids ratio. This is the starting point the study compared everyone against.
G/T One copy of the version the research linked to Polyunsaturated fatty acids to monounsaturated fatty acids ratio. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Polyunsaturated fatty acids to monounsaturated fatty acids ratio. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source
GWAS and multi-omics integrative analysis reveal novel loci and their molecular mechanisms for circulating fatty acids
Sun Y, Xu H, Ye K
HGG advances · 2025 · PMID 40545721 · open access

Questions about rs17481744

What is rs17481744?

rs17481744 is a single position in the genome, in or near the CSGALNACT1 gene. Published research associates it with polyunsaturated fatty acids to monounsaturated fatty acids ratio. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs17481744 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs17481744 come from?

GWAS Catalog, HGG advances 2025, PMID:40545721. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Polyunsaturated fatty acids to monounsaturated fatty acids ratio (rs17481744). MyGeneLog™. https://www.mygenelog.com/variants/rs17481744

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