0 503329122226Reads by AI crawlersClaude3ChatGPT3Google · Gemini0Perplexity2Meta AI9Microsoft · Copilot1Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others26Total50Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 97 European ancestry thyroiditis cases, 107 European ancestry ankylosing spondylitis cases, 100 European ancestry psoriasis cases, 173 European ancestry celiac disease cases, 254 European ancestry systemic lupus erythematosus cases, 308 European ancestry common variable inmunodeficiency cases, 865 European ancestry ulcerative colitis cases, 1,086 European ancestry Type 1 diabetes cases, 1,123 European ancestry juvenile idiopathic arthritis cases, 1,922 European ancestry Crohn's disease cases, 10,718 European ancestry controls.
The effect
The reported allele is G; the catalogue records no effect size
; p = 3 × 10−10.
How common The G allele had a frequency of about 2% in the people studied.
Where it sits Chromosome 12, band 12q12 — in an intron of LRRK2.
What ClinVar records
ClassificationLikely benign; criteria provided, multiple submitters, no conflicts (2 of 4 stars, 2 submitters), last evaluated 2018-08-14.
ClinVar record 1198417NM_198578.4(LRRK2):c.7391-177A>G
What this is ClinVar's aggregate record for this position (as of its 2026-10-19 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.
What each result means
A/ANo copy of the version the research linked to Pediatric autoimmune diseases. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Pediatric autoimmune diseases. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Pediatric autoimmune diseases. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs17466626 is a single position in the genome, in or near the LRRK2 gene. Published research associates it with pediatric autoimmune diseases. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs17466626 linked to?
On MyGeneLog this position is linked to Ulcerative Colitis. The research behind each link, and its sources, are set out on that condition page.
Does having rs17466626 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs17466626 come from?
GWAS Catalog, Nat Med 2015, PMID:26301688. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 503329122226Reads by AI crawlersClaude3ChatGPT3Google · Gemini0Perplexity2Meta AI9Microsoft · Copilot1Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others26Total50Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.