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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 2,045 European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.218 lower (95% confidence interval 0.15-0.28); p = 6 × 10−11.
Where it sits Chromosome 11, band 11q12.2 — a synonymous change in FADS3.
What each result means
C/CNo copy of the version the research linked to Phosphatidylcholine levels. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Phosphatidylcholine levels. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Phosphatidylcholine levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2019 · PMID 31551469 · open access
Questions about rs174465
What is rs174465?
rs174465 is a single position in the genome, in or near the FADS2 gene. Published research associates it with phosphatidylcholine levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs174465 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs174465 come from?
GWAS Catalog, Nature communications 2019, PMID:31551469. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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