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Regional cortical thickness (precuneus)

STRN · rs17443495

What the study found

Who was studied 34,559 European ancestry individuals.

The effect The reported allele is C; the catalogue records no effect size ; p = 2 × 10−10.

Where it sits Chromosome 2, band 2p22.2 — in an intron of STRN.

What each result means

C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Regional cortical thickness (precuneus) compared to the general population.
C/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Regional cortical thickness (precuneus).
G/G Published research associates this genotype with typical/baseline likelihood of Regional cortical thickness (precuneus) — no copies of the reported risk allele.
Source

Questions about rs17443495

What is rs17443495?

rs17443495 is a single position in the genome, in or near the STRN gene. Published research associates it with regional cortical thickness (precuneus). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs17443495 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs17443495 come from?

GWAS Catalog, Nature communications 2024, PMID:38890310. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Regional cortical thickness (precuneus) (rs17443495). MyGeneLog™. https://www.mygenelog.com/variants/rs17443495

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