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C-reactive protein

TRAF3IP2 · rs174401

Where this position leads

Condition: C-Reactive Protein Levels

rs174401 Condition: C-Reactive Protein Levels C-Reactive Protein Levels Condition rs174401 rs174401 TRAF3IP2

What the study found

Who was studied 353,466 European ancestry individuals, 83,025 East Asian ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0147 lower (95% confidence interval 0.0096-0.0198); p = 1 × 10−8.

Where it sits Chromosome 6, band 6q21 — in an intron of TRAF3IP2.

What each result means

C/C No copy of the version the research linked to C-reactive protein. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to C-reactive protein. That is a smaller link than two copies.
T/T Two copies of the version the research linked to C-reactive protein. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs174401

What is rs174401?

rs174401 is a single position in the genome, in or near the TRAF3IP2 gene. Published research associates it with c-reactive protein. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs174401 linked to?

On MyGeneLog this position is linked to C-Reactive Protein Levels. The research behind each link, and its sources, are set out on that condition page.

Does having rs174401 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs174401 come from?

GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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C-reactive protein (rs174401). MyGeneLog™. https://www.mygenelog.com/variants/rs174401

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